They say it's always darkest just before the dawn, and after several seasons of offscreen actor complications and onscreen moping by some major characters, Grey's Anatomy has had a genuine creative renaissance. The cast is dense with deep, richly textured characters, almost of all of whom are capable of shouldering major storylines that keep audiences intrigued, and the writers keep innovating new emotional twists and medical mysteries. Seattle Grace is going to be around for the long haul, and that's only good news. (Also, we love you, Lexipedia!)