The event, formerly known as the MTV Movie Awards, will air live from Los Angeles on May 7.
Noah, Miley Cyrus' 17-year-old sister released her debut single, "Make Me (Cry)," last November. She will perform her second single at the 2017 MTV Movie &TV Awards. Both are featured on her upcoming debut album NC-17.
"I'm so excited to be performing at the MTV Movie & TV Awards,'" she said in a statement released by MTV. "It will be my first time performing "Stay Together" on TV and I'm looking forward to having a great time!"
Noah had also been performed at the recent 2017 Radio Disney Music Award and the 2017 iHeartRadio Music Awards. and Miley introduced her at the latter, saying, "Her voice is amazing, her songwriting is beautiful and relatable. She knows who she is as an artist and I can't wait for the whole world to get a load of her vision. She's who I want to be when I grow up, and that's saying a lot, 'cause she's younger than me. Get ready, because 2017 is about to be Noah's year."
Meanwhile, at the 2017 MTV Movie & TV Awards, Big Sean will perform his new single, "Jump Out the Window," from new album, "I Decided."
He and Noah join previously announced performers J Balvin, Pitbull and Camila Cabello, who will take the stage together at the show to perform their new single, "Hey Ma," which is featured on the soundtrack of The Fate of the Furious.
The movie, the eighth film in the franchise, will receive the Generation Award at the ceremony. Main actor Vin Diesel will accept the honor on behalf of the cast. This marks the first time the award will not be given to an individual star.
Other 2017 MTV Movie & TV Award nominees include Jordan Peele's hit movie Get Out, which received six nods, Disney's new live-action Beauty and the Beast and its stars Emma Watson, Dan Stevens, Josh Gad and Luke Evans, Stranger Things and main star Millie Bobby Brown and This Is Us stars Mandy Moore, Milo Ventimiglia, Chrissy Metz and Lonnie Chavis.