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Garry Shandling

Jason LaVeris/FilmMagic

Garry Shandling has died at age 66.

The Los Angeles Police Department confirms to E! News the actor and comedian—who is known to have influenced the likes of Ricky Gervais, Jon Stewart, Judd Apatow and more—passed away on Thursday at a hospital in Los Angeles.

E! News learned the Los Angeles Fire Department responded to a medical emergency at 10:40 Thursday morning for an address listed under Shandling. The patient was then transported to Providence Saint John's Health Center by ambulance and was alive at the time of transport. He passed away at the hospital.

Shandling was most known for his work on The Tonight Show Starring Johnny Carson, frequently appearing as a guest. He also created It's Garry Shandling's Show in 1986 which lasted until 1990, seeing several Emmy nominations.

Garry Shandling

Tiffany Rose/Getty Images for Harold & Carole Pump Foundation

His second show, The Larry Sanders Show, saw even more success when it began airing in 1992. He ended up being nominated for 18 Emmy Awards for the show and saw a win in 1998.

Shandling will appear in The Jungle Book movie, which is set to premiere on April 4th, hitting theaters on April 15th.

He most recently appeared on his old friend Jerry Seinfeld's web-series, Comedians in Cars Getting Coffee, in January. His last photo on social media was of him spending time with Kathy Griffin and Bob Odenkirk on Sunday, March 20. Griffin shared the photo from the outing.