Kevin Winter/Getty ImagesSam Smith and Jimmy Napes can now add the title of "Oscar winner" under their belts, after winning Best Original Song for "Writings on the Wall."
The song was featured in the latest installment of the James Bond franchise, Spectre.
Smith shouted out his fellow artists nominated in the category, including the "incredible" Lady Gaga, and dedicated his award to the LGBT community.
"I read an article a few months ago by Sir Ian McKellen, and he said that no openly gay man had ever won an Oscar," said Smith.
"If this is the case, even if it isn't the case, I want to dedicate this to the LGBT community all around the world."
Smith added: "I stand here, I stand here tonight as a proud gay man and I hope we can all stand together as equals one day."
The award was presented by last year's winners for Best Original Song, Common and John Legend, who won for "Glory," which was featured in the film Selma (2014.)
The other nominees for Best Original Song this year included:
"Earned It," Fifty Shades of Grey, Abel Tesfaye, Ahmad Balshe, Jason Daheala Quenneville and Stephan Moccio
"Manta Ray," Racing Extinction, J. Ralph and Antony Hegarty
"Simple Song #3," Youth, David Lang
"'Til It Happens to You," The Hunting Ground, Diane Warren and Lady Gaga
The ceremony featured performances from several of the category's nominees earlier in the evening.
The Weeknd slayed "Earned It" with a seriously sexy performance featuring scantily clad dancers and a trapeze artist.
Smith crooned "Writing's on the Wall" for the Oscars crowd, and Lady Gaga delivered a powerful performance of "'Til It Happens to You."
Don't miss the E! Live After Party at 11:45 p.m. ET / 8:45 p.m. ET. On Monday, watch a special edition of E! News at 7 and 11 p.m., and catch the Fashion Police Oscars special at 8 p.m.