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Megan Mullally, Sean Hayes, NBC, James Burrows Special

Art Streiber/NBC

Jack and Karen, together again! Sean Hayes and Megan Mullally were on hand to celebrate legendary Will & Grace director James Burrows and E! News has your first look at this reunion. Nostalgia never felt (and looked) so good.

Hayes, Mullally and costar Eric McCormack were just some of the many stars who came together for NBC's Must See TV: An All Star Tribute to James Burrows. Burrows recently directed his 1,000th episode of TV, an episode of NBC's upcoming comedy Crowded. He's been behind the camera on some of your favorite shows, including The Mary Tyler Moore Show, Friends, Mike & Molly and Frasier. To honor Burrows, the casts many of those shows and more assembled for a taped tribute and retrospective.

"There is nobody with better TV comedy instincts than Jimmy Burrows, and because of his guiding hand these remarkable shows will be forever celebrated and stand the test of time," Paul Telegdy, president of alternative and late night programming at NBC Entertainment, said in a statement when the special was originally announced. "The caliber of talent joining us to celebrate Jimmy's accomplishments is a testament to his imprint in television history."

Megan Mullally, Sean Hayes, Will & Grace

Chris Haston/NBC/NBCU Photo Bank via Getty Images

Besides the cast of Will & Grace, here's who else is getting together:

Friends Jennifer Aniston, Courteney Cox, Lisa Kudrow, Matt LeBlanc and David Schwimmer with a pre-taped segment from Matthew Perry.

CheersTed Danson, Shelley Long, Bebe Neuwirth, Rhea Perlman, John Ratzenberger and George Wendt, with Kirstie Alley and Woody Harrelson in pre-taped segments.

TaxiTony Danza, Danny Devito, Marilu Henner, Judd Hirsch, Carol Kane and Christopher Lloyd.

The Big Bang TheoryKaley Cuoco, Johnny Galecki, Simon Helberg and Jim Parsons.

WingsTony Shalhoub and Steven Weber.

Mike & MollyBilly Gardell, Melissa McCarthy, Katy Mixon, Nyambi Nyambi and Reno Wilson.

Two and a Half MenJon Cryer and Charlie Sheen.

CrowdedCarlease Burke, Stacy Keach, Carrie Preston, Mia Serafino and Patrick Warburton.

JB Smoove, Jason Bateman, Valerie Bertinelli, Kate Flannery and Will Arnett will also appear. Bob Newhart will also appear in a pre-taped segment. See some of the attendees in our new gallery.

Along with his appearance as part of the Will & Grace cast, Sean Hayes also executive produced the special with his producing partner Todd Milliner and John Irwin.

The special airs Sunday, Feb. 21 at 9 p.m. on NBC.

(E! and NBC are both part of the NBCUniversal family.)