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With "virtually no one" in Hollywood refusing to make a cameo appearance in the upcoming Zoolander sequel, it might have seemed pretty simple to book Jennifer Aniston(whose husband stars in and co-wrote the flick) for the gig. 

Think again. 

Speaking with E! News' Erin Lim in New York City over the weekend, Justin Theroux revealed not even he could convince the A-lister, joking, "I couldn't even get past her agent. Then I tried to get to her manager, couldn't get to her manager. I didn't want to bring it up at the house."

Jennifer Aniston, Justin Theroux, Critics Choice Awards

Jason Merritt/Getty Images

Turns out Jen's busy schedule kept her from flying to Rome where Zoolander 2 stars Ben Stiller, Will Ferrell and Kristen Wiig were filming. 

In between reuniting with her Friends castmates for an NBC special set to air later this month, Jen will also be celebrating her 47th birthday and Valentine's Day.

As for the lovebirds' big plans? 

"We're gonna probably just do what you do," Theroux dished. "Have a nice dinner on the birthday, have a nice romantic dinner on the Valentine's Day, and we'll see."

Don't miss Zoolander 2 when it hits theaters this Friday.