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Angelina Jolie,  Kids Choice Awards 2015

Lester Cohen/KCA2015/WireImage

The 2015 Kids' Choice Awards brought about a lot of screams, laughs, pies and of course, slime! But it was Angelina Jolie's moving speech that brought inspiration to the audience at Saturday's awards show.

The 39-year-old actress, who made her first post-surgery appearance with kids Zahara and Shiloh at the show, reminded fans of all ages to never be afraid of being "different" after accepting her award for Favorite Villain.

The Maleficent star shared with the audience that growing up, she was never one to fit in with the crowd. As a result, she learned to embrace being different from the rest.

"Different is good. So, don't fit," the mother of six said. "Don't ever try to be less than what you are, and when someone tells you that you are different, smile and hold your head up high and be proud."

And of course, Jolie wouldn't have won the award for Favorite Villain if she didn't finish her speech in true villain style!  "Cause a little trouble. It's good for you," she added before a bunch of slime fell onto a few unsuspecting kids.

Nolan Gould, Jesse Tyler Ferguson, Rico Rodriguez, Sarah Hyland, Ariel Winter

Kevin Winter/Getty Images

Take a look at who else won a special award at Saturday's big show. 

Favorite Villain: Angelina Jolie

Favorite Male Singer: Nick Jonas

Favorite Reality Show: Dance Moms

Favorite Talent Competition Show: The Voice

Favorite Book: Diary of a Wimpy Kid series

The Most Addicting Game: Minecraft

Favorite Female Singer: Selena Gomez

Song of the Year: "Bang Bang" by Jessie J, Ariana Grande & Nicki Minaj

Favorite Music Group: One Direction

Favorite Animated Movie: Big Hero 6

Favorite Female Action Star: Jennifer Lawrence

Favorite Movie Actor: Ben Stiller

Favorite Movie: The Hunger Games: Mockingjay— Part 1

Favorite Male Action Star: Liam Hemsworth

Favorite New Artist: Fifth Harmony

Favorite Cartoon: Spongebob Squarepants

Favorite TV Actor: Ross Lync

Favorite TV Actress: Laura Marano

Favorite Kids TV Show: Austin & Ally

Favorite Family TV Show: Modern Family

Favorite Movie Actress: Emma Stone