Courteney Cox is looking to her friends for help with her latest cause.

The Dirt star and her husband, David Arquette, have recruited a roster of famous folks, including Jennifer Aniston, to help them try to raise $1 million in two weeks for Epidermolysis Bullosa, a rare and debilitating skin condition that primarily affects children.

"EB is very personal to me, so I'm happy to be a part of this $1 million challenge," Cox said in a statement. "Now is such an important time to put the spotlight on EB and ensure that research can continue at a fast pace."

Aniston's ex, Brad Pitt, is also on board for the challenge, as are Gwen Stefani, Gavin Rossdale, Orlando Bloom, Kate Beckinsale, Rashida Jones, James Marsden and Eva Longoria Parker.

Cox and Arquette are heading up the effort as members of the honorary advisory board of the Epidermolysis Bullosa Medical Research Foundation. Aniston, Pitt, Rossdale and Stefani are also members.

Those affected by the condition break out in painful blisters after even minor trauma to the skin. Wounds may cover up to 75 percent of the body and never go away.

Few people who suffer from Epidermolysis Bullosa survive past the age of 30. As many as 100,000 Americans may have some form of the condition.

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