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What would Joshua Jackson do?

Or rather, what would you do if you picked up the phone and Morgan Freeman's distinctive deep voice greeted you on the other end of the line? In the Stand Up to Cancer promo above, the former Fringe star admits he might pass out.

Maybe you'd join him in losing consciousness?

Stand Up to Cancer is airing on all major networks, including E!, on Sept. 5. The star-studded telecast—which has raised $261 million to date—is entering its fourth fundraising year, and when Hollywood hits the phone banks during the show, it could be Freeman, Jennifer Aniston, Halle Berry, Gwyneth Paltrow and many more celebs giving you a swoon-worthy shout out, but first they'll need your number.

As we await the highly anticipated telethon, sign up at werecallingyou.org with your seven digits to receive your charitable call, describe your connection to cancer and tune in as Ariana Grande, Jennifer Hudson, Common and others entertain you for a great cause.