The Oscar winner addressed more than 300 government officials at the Global Summit to End Sexual Violence in Conflict in London, where she was asked about the part in the movie where her character's wings are brutally ripped off of her body by a friend as she sleeps.
"We were very conscious, the writer [Linda Woolverton} and I, that it was a metaphor for rape," she explained.
"This would be the thing that would make her lose sight."
The UN Special Envoy added, "At a certain point, the question of the story is what could possibly bring her back?"
The 39-year-old is co-hosting the four-day conference with her frequent collaborator, William Hague, England's Foreign Secretary.
"It is a myth that rape is an inevitable part of conflict," she said during her main speech at the summit.
"There is nothing inevitable about it. It is a weapon of war aimed at civilians. It is nothing to do with sex, everything to do with power…This whole subject has been taboo for far too long, war zone rape is a crime that thrives on silence and denial."
Jolie also told reporters that she and Hague had spoken about a woman they met in Bosnia who was too ashamed to tell her son that she had been raped.
"This day is for her. We believe it truly is a summit like no other."