According to The Independent, the United Nations Goodwill Ambassador "became the subject of controversy in China, after she labelled film director Ang Lee Taiwanese, not Chinese, inadvertently embroiling herself in complex cross-Strait relations."
The Oscar winner was asked who her favorite Chinese director is, to which she replied, "I am not sure if you consider Ang Lee Chinese, he's Taiwanese, but he does many Chinese-language films with many Chinese artists and actors."
She added, "I think his works and the actors in his films are the ones I am most familiar with and very fond of."
Jolie's public remarks have sparked major backlash in China, with many commenters and Chinese outlets calling for a boycott on the actress and a ban on the release of her Disney film.
One user of the popular Weibo platform reportedly called the A-lister a "deranged Taiwan independence supporter."
The turn of events comes on the heels of the Chinese government letting her fiancé, Brad Pitt, into the country to join her on her press tour for the flick.
Pitt was originally banned from the country after filming Seven Years in Tibet in 1997.
Maleficent has yet to be released in China, but has been in the No. 2 spot in Taipei since opening in theaters on May 30.