The untitled action-comedy stars Witherspoon as a straitlaced policewoman protecting a drug lord's sexy widow, played by Vergara, as they run from crooked cops and murderous criminals through the Lone Star State.
And the blonde-brunette duo looks to be enjoying their roles in the photos they shared on Instagram today.
The Legally Blonde star posted a pic of her in full uniform playing with a furry costar's big ears, writing "Dog casting on set #bassetthound#allears."
But the Modern Family actress opted to snap a pic posing in her movie star chair with her son smiling behind her, which she captioned "On the set."
The Anne Fletcher gal-pal buddy film is shooting on location in New Orleans and will be released on Mother's Day weekend next year on May 8.