Rocking a cozy cardigan, loose-fitting tank and distressed jeans, the cover girl reveals she doesn't buy into Hollywood's obsession with expectant stars' bodies.
"You're not supposed to look perfect while you're making babies—making babies is the perfection," says Barrymore, who is pregnant with her second child with husband Will Kopelman.
And when it comes to post-baby bodies, the 38-year-old doesn't subscribe to the notion that a woman has to bounce back as soon as she's given birth, either.
"It's about feeling good in clothes and knowing you can get dressed up in an evening and work it for a minute," she explains. "You know, maybe get back into a certain pair of jeans, but there's just no such thing as perfection. If you're trying to get there, you're just torturing yourself."
Similarly, the star, who launched makeup line Flower earlier this year, suggests women give themselves a break when it comes to their beauty routines.
"My main beauty tip is don't say that negative thing when you look in the mirror. It just isn't healthy," she advises. "That lack of beating up on ourselves—that's my new mantra. Happiness is the best makeup; a smile is better than any lipstick you'll put on."
Pretty refreshing, huh?
But for those of us would like a little boost with the help of makeup, Barrymore also offers tips for recreating beauty looks based on her fave florals—cabbage rose, red dahlia and a purple orchid—in the magazine, which hits newsstands later this month.