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Amanda Righetti, Owain Yeoman, The Mentalist

Richard Foreman/Warner Bros.

First Cote de Pablo jumps the NCIS ship and now this? Oh, it breaks a TV fan's heart.

The Mentalist's Amanda Righetti and Owain Yeoman, who play special agents Grace Van Pelt and Wayne Rigsby, will exit the CBS drama at the end of this upcoming sixth season, TVLine is reporting.

"I can neither confirm or deny," series creator Bruno Heller said in a statement. "But this is the most dramatic and game changing season and anything can happen."

The pair, whose on-again/off-again relationship went back to on again in the season-five finale, have been with The Mentalist since the pilot episode. Their departure from the series might revolve around the unmasking of Red John, which CBS promised would be revealed by the end of 2013.

CBS and Warner Bros. have no comment on Righetti and Yeoman's exit.

The Mentalist returns on Sunday, Sept. 29, at 10 p.m.