Jason Segel, Alyson Hannigan, Neil Patrick Harris, Cobie Smulders, Josh Radnor, How I Met Your Mother

Jeffrey R. Staab/CBS

How I Met Your Mother is going to Comic-Con for the first (and last) time!

20th Century Fox TV is sending the cast and creators of the hit CBS sitcom to San Diego Comic-Con 2013 this July to preview the final season (Sniff!), and the panel will include Josh Radnor, Jason Segel, Cobie Smulders, Neil Patrick Harris and Alyson Hannigan, as well as executive producers Carter Bays, Craig Thomas and Pamela Fryman. Hmm...could the mother, aka Cristin Milioti, also make a surprise appearance?

And though Fox is sending 11 programs to the Con, Glee, a show which once held a panel in the famed Hall H, will be sitting the 2013 season out!

On Thursday, July 18, fans can attend the Murder Police panel, an animated series from Family Guy's David Goodman, as well Bob's Burgers and Brickleberry's panels. Alex Kurtzman and Roberto Orci's highly anticipated new drama series Sleepy Hollow will hold an exclusive world premiere screening of the pilot, as well as a Q&A with stars Tom Mison and Nicole Beharie on Friday, July 19. David Boreanaz and executive producers Hart Hanson and Stephen Nathan will once again return to The Con to provide scoop and never-before-seen footage to Bones fans.

In addition to How I Met Your Mother's Comic-Con debut, Fox will host Saturday panels for Futurama, Family Guy, American Dad and The Simpsons. Homer and Bart's Springfield-set 'toon will be celebrating its 25th year by showing  fans never-before-seen footage from guest director Giullermo del Toro.

FX's gritty biker drama Sons of Anarchy will help close out the nerdtastic weekend with a panel on Sunday that will include creator Kurt Sutter and stars Charlie Hunnam, Katey Sagal, Ron Perlman, Maggie Siff, Kim Coates, Mark Boone Junior, Tommy Flanagan, Theo Rossi, Dayton Callie and Jimmy Smits.

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