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Charlie Sheen, Holland Taylor, Ashton Kutcher

AP Photo; Getty Images; WireImage

Holland Taylor is sounding off on her Two and a Half Men pals Charlie Sheen and Ashton Kutcher.

In a new interview with Parade, the 70-year-old actress shares her thoughts on her two headline-making costars.

"Anybody who's spent time with Charlie likes him," Taylor gushed of Sheen, who played her son on the hit CBS show. "He's as smart a person as you'll ever find."

When asked about some Sheen's not-so-smart decisions, Taylor said, "He grew up with a movie star father [Martin Sheen] who was gallivanting around the world. [Today] Martin is a big AA person and very public about it. But back in the day, Martin was a young, crazy, brilliant talent—always gone, always traveling, sometimes bringing his kids along."

"It was just a madhouse way [for Charlie] to grow up," she continued. "And then Charlie himself was a teenage movie star with hundreds of thousands of dollars in his pocket at any given moment. It sounds great to a lot of people, but it's not that easy to mature and to have a regular life."

As for Kutcher, Sheen's Two and a Half Men replacement, Taylor dished, "He's very charming. Very affable and smart. But I've hardly been exposed to him at all."

Taylor also reveals that she "suffered depression" from her "early 40s into my mid-50s."

"[It was] bad enough for me to entertain the idea of going into a hospital. I actually wasn't a danger to myself, but I really sometimes wondered how I could get out of the house to go get food. I was on antidepressants for over 15 years, with very intermittent counseling. It was a very dead period of my life. Antidepressants take away the lows but they also reduce the highs. And for me, over a long period of time, they didn't really work. So I quit taking them, and my life has been afire since then."