Guess we won't be seeing an encore of the boob song next year.
"Traumatized critics exhale: I'm unable to do the Oscars again. Tried to make it work schedule-wise, but I need sleep," the Family Guy mastermind tweeted.
Family Guy also reportedly made a humorous reference to the MacFarlane's decision on last night's season finale, an episode called "Road to Vegas: No Country Club for Old Men," with a cutaway to "Stewie hosts the Oscars."
For the Academy of Motion Picture Arts & Sciences, having MacFarlane back would've been a double-edged sword in any case.
On one hand, he wasn't exactly killing it in the ratings as the 40.3 million in viewers who tuned into his wisecracks was barely an improvement over 2012's ceremony, which drew an anemic 39.3 million with Billy Crystal's return.
On the other hand, his stint as emcee definitely delivered on controversy, most notably with his irreverent homage to onscreen female nudity in his opening number "We Saw Your Boobs" which Fonda, Davis and Curtis deplored and quips via his Ted alter ego about Jews controlling Hollywood, which drew condemnations from various Jewish groups.
Now that MacFarlane's out, no word who Zadan and Meron are considering for the gig.
As for Joaquin, given his already well-known distaste for the awards (he previously called the Oscars "bulls--t" and the "stupidest thing in the whole world"), we imagine he'd pass on it as well.