Her courage to go public has everyone thinking—and talking.
This certainly isn't the first time Jolie has used her celebrity platform to help change the world. From the Jolie-Pitt Foundation to her work with UNHCR, Jolie's impact is felt here in the U.S. and abroad.
Here, we shine a light on just some of Jolie's activism and philanthropic work.
Women's and Children's Rights: Most recently, Jolie donated $200,000 to 15-year-old Malala Yousafzai's fund to promote women's rights to education in Pakistan after the teen survived a brutal attack by the Taliban that included getting shot in the head. At about the same time, Jolie announced she has opened an all-girls primary school in Afghanistan outside of Kabul. Profits from her jewelry collection, the Style of Jolie, will go to build more schools around the world.
Animal Endeavors: After spending Christmas at the N/a'an ku se Sanctuary's wildlife lodge in daughter Shiloh's birth country of Nambia, Jolie and Pitt pledged a whopping $2 million to support the animal group's work supporting land conservation and the protection of wildlife in the area.
Disaster Relief: Jolie and Pitt gave $500,000 to help rebuild the town of Joplin in Pitt's home state of Missouri after 30 percent of the buildings were destroyed and 150 people were killed by a tornado in 2011. The couple also donated $1 million to help earthquake relief efforts in Haiti and hosted a charity dinner in the tony Hamptons to raise funds for victims still in need of housing two years after Hurricane Katrina.
Gay Rights: Jolie and Pitt have said they wouldn't marry until everyone is allowed to wed in the U.S. While the lovebirds seemed to have had a change of heart when they announcement their engagement a little over a year ago, at least one gay rights group supported their wishes, arguing that getting hitched doesn't lessen their support for marriage equality.
Refugee Aid: Jolie has visited dozens of countries and refugee camps since she began working with the United Nations High Commissioner for Refugees in 2001. Villa Angelina, a U.S.-funded apartment building named after Jolie, opened about two years ago in Rogatica, Bosnia for refugees of the 1992-1995 war in Bosnia and Herzegovina.