Culkin's publicist confirmed Friday that the onetime kiddie star has "temporarily" separated from his wife of two years, Rachel Miner.
"It was very amicable and they remain the best of friends," Paul Bloch said. Bloch would not say if the couple was living apart, and they're not presently planning to divorce.
Culkin, now 19, is currently in London trying to jump-start his long-dormant acting career by starring in a play. (Culkin's last film was the 1994 bomb The Pagemaster.)
Also a former child actor, Miner, 20, struck up her romance with the Home Alone star in 1997, after the two met while attending the Professional Children's School in Manhattan. She is best known for costarring with Natalie Portman in Broadway's The Diary of Anne Frank and for playing Michelle Bauer on CBS's The Guiding Light from 1989-1995.
The couple married in June 1998, when both were just 17.