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Mary Tyler Moore, Valerie Harper

Kevin Winter/Getty Images

Actress Valerie Harper may have a positive outlook on her diagnosis of terminal brain cancer, but her on-and-off-screen BFF Mary Tyler Moore can't help but feel down. 

"I'm absolutely devastated by this news," the The Mary Tyler Moore Show star, who underwent surgery for a brain tumor in May 2011, told E! News in a statement. "Valerie has given so much joy, laughter and love to the world. I join her fans and send much love and positive thoughts to her and her family during this difficult time."

Harper recalled phoning Moore the day before her news went public.

Mary Tyler Moore, Valerie Harper, Rhoda


"She said, 'What's up?' I said, 'It's incurable cancer.' She said, 'Val, I'm so sorry,'" Harper told the mag, who first broke the news in its latest issue. Before ending their phone call, "Mary said, 'One day at a time,'" says Harper. "That's how we've got to live our lives. That's the best we can do."

Harper explained that numerous tests showed she had leptomeningeal carcinomatosis, a rare disorder in which cancer cells metastasize into the fluid-filled membrane enveloping the brain. Doctors have given her "as little three months left to live."

"I don't think of dying," she told People. "I think of being here now."