The talk-show veteran and Real Housewives of Atlanta star will be filling in for the CNN journalist on Anderson Live, who is currently in the Middle East, for Monday's show (yes, tomorrow).
"I will fill in for Anderson cooper on his show Monday - as he is on assignment in Israel - nene leeks is my co host - #tweeted.," O'Donnell
NeNe also tweeted, "Tune in Monday 2 I will co-host wit my boo Anderson Cooper."
Cooper will be chiming in via satellite to give the latest report on what's happening with the conflict in Israel. Meanwhile, the dynamic duo will tackle the latest news and discuss the film Lincoln with guest James Spader.
Are you excited to see Rosie and NeNe take on Anderson Live? Sound off in the comments!