The Dancing With the Stars hopeful, who is no stranger to talk about her own weight struggles, came out roaring in defense of the pop superstar amid criticism that the "Alejandro" singer had packed on some pounds.
"I say more power to her," Alley told OK! magazine Tuesday after DWTS' results show.
"She is such a role model for millions of girls in the world and she should be whatever weight she wants to be and nobody should have to starve themselves."
Alley also brushed off talk of Gaga's fuller figure—"She gained, what, 30 pounds? Who cares!"—and praised the singer for urging fans to stand up for themselves and their bodies.
"I think it's good that she's saying this and starting the body revolution."
One designer, meanwhile, is celebrating Gaga's gorgeous curves.
Thierry Mugler creative director Nichola Formichetti has released a new line of handbags that reportedly pays homage to Mama Monster's derrière.
"She doesn't know yet," the designer tells Women's Wear Daily, adding that the line "has a little bit of punk-rock feeling, but it's still quite chic."
Formichetti, whose new handbag collection features a sultry, curvy silhouette, has a close connection with Gaga, having styled several of the pop star's fashion shoots and music videos.
Gaga bravely tackled talk about her weight earlier this week by posting a photo of herself in her underwear with the caption "Bulimia and anorexia since I was 15," as well as creating a new channel on her site called "Body Revolution."
Indeed, Mama Monster is making good on her promise to empower fans to be proud they were born this way.