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Giuliana Rancic on IVF Treatment: "Third Time's a Charm!"

Giuliana Rancic John Lamparski/WireImage

Giuliana Rancic has unsuccessfully gone through in vitro fertilzation twice now in hopes of having a baby, but she's not giving up just yet.

The E! News and Fashion Police host tells me that she and hubby Bill Rancic will give the treatment another go.

"We're definitely going to do IVF again in the near future," G. told me while hosting Nivea's 100 Year Haus party in NYC yesterday. "If it doesn't work, that will have been three times—but I think third time's a charm. I feel good about the third time!"

Fingers crossed that it works for her, but if not, they know they'll have a child one way or another...

PHOTOS: Giuliana's Wardrobe

"At that point, we will either do surrogacy or go right to adoption," she explained, adding that her hometown of Naples, Italy, would be the first place they'd look to adopt.

"I would love to find some kid in the area...someone, anyone who needs a home and give them a life here in America," Giuliana shared. "The thing with adoption is, it's where your heart takes you. Like when Angelina Jolie adopted from another country...How can you tell a woman where she should go look for her baby?"

The couple's doctor also agrees that they should try IVF one final time.

Although Giuliana conceived the second time they tried the procedure, sadly she miscarried. But the TV personality says it's not hard to stay positive despite their setbacks.

"Yes, I was very ill for a couple of weeks," she explained of the last round of IVF. "But if I end up getting pregnant and having a baby, I'm sure I'll forget all about it."

"It's very easy to just be sad and feel bad for yourself and get a lot of attention for it," she said. "Mourn, be sad. But then you have to look at the positive. There are so many amazing things in my life. It's not my job; it's not Fashion Police. That's not what makes me happy. What makes me happy truly is when I drive in my car in the morning. I turn the radio off and I just say out loud what I'm grateful for."

And it's not her Style Network reality show Giuliana & Bill or her Range Rover she appreciates most.

"I say thank you for my health. Thank you that I have a comfortable bed to sleep in and a roof over my head. We are so lucky that I can't feel sorry for myself. I'm so lucky to have Bill and I'm lucky to have a beautiful family."

Here's hoping this amazing couple will add to that family very soon!

WATCH: Giuiliana and Bill's big date

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