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Mickey Rourke, The Wrestler, Sean Penn, Milk, Brad Pitt, The Curious Case of Benjamin Button

Niko Tavernise / Fox Searchlight; Phil Bray / Focus Features; Paramount Pictures

If you believe the buzz, the Academy Award for this Best Actor thing is a three-way race. Or even a two-man smackdown (sorry, Brad Pitt). Or even maybe a lock for Sean Penn. Whatever, it'll all be worked out on Sunday.

But for now, you make the call. Then check out our interactive prediction poll to make picks in other categories—and see what E! Online columnists say.

Take the entire E! Online Oscar Prediction Poll!