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Oprah Winfrey

Frederick M. Brown/Getty Images

She already hosts an über-successful talk show, so is it any surprise Oprah's been tapped to host fashion's biggest fete?

The Big O is teaming up with Vogue editor-in-chief Anna Wintour for the Met's Costume Institute Gala on May 3.

She's definitely in good company. Last year, Kate Moss and Justin Timberlake had emceeing honors. The annual fashion soiree always brings out the A-listers clad in their craziest couture.

It sounds like Oprah's already working on her fitness for the big event...

In an interview with E! News' Giuliana Rancic, Oprah took questions from Twitter users—for example, "In the past 24 hours, what have you done for your physical health?"

"This morning I did treadmill, ran around the track at East Bank and did weights," Oprah told G of her routine.

As for Oprah's secret talent?

"I am really, really great at spot removal," she dished. "I have a young dog. And I'm very good at stain removal."

So she can take over the world and then tackle your laundry...is there anything the superstar can't do?

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You must see what celebs wore this year. Check out their collection of wild outfits in our 2009 Met Costume Institute Gala gallery.