Calling an adorable pet their very own and raising awareness for jam-packed animal shelters? All in a day's work for Hollywood's most compassionate celebs.
In honor of E! News' Celebrity Pets Week, click through the gallery below to see 40 A-listers who've become totally inseparable from their furriest friends since rescuing them. We raise a glass paw to those that have walked the extra mile in providing a brighter future for their lovable animals!